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Day and night are regular occurrences in nature, and the organs and tissues in living bodies follow this cycle. The sympathetic nervous system (SNS) at various time points regulates organ excitation to maintain healthy functions in the living body. The energy required from basal metabolism can be used to explain living organisms according to the traditional Chinese medicine (TCM) concept of relationships between meridian directions and organs at various times (organs “at rest” and organs “in operation”).  By monitoring skin reactions after applying a cream, we speculated regular blood flow changes, and established an animated hourglass-shaped trajectory diagram to visualize these changes. A combination of TCM and physiological perspectives were considered to explain how the cardiovascular system produces energy. These two perspectives were applied to interpret the correlation between the SNS and organ metabolism

Stratum Corneum Hydration and Skin Surface pH Variation Indicate that Organ Blood Flow Is Regulated by Meridian Activity at Certain Hours