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Four new peptides were isolated from the culture broths of the marine-derived fungi Aspergillus  allahabadii and A. ochraceopetaliformis. Based on the results of chemical and spectroscopic analyses, two compounds ( 1 and 2 ) from A.  allahabadii were determined to be cyclopentapeptides, while those from A. ochraceopetaliformis were a structurally-related cyclodepsihexapeptide ( 3 ) and its linear analog ( 4 ). In addition to the presence of a D-amino acid residue, the almost reversed sequence of peptides in 3 and 4 , relative to those of the 1 and 2 , is notable. These new compounds exhibited moderate inhibition against the enzyme sortase A as well as a weak inhibition against isocitrate lyase ( 2 ).

New Peptides from The Marine-Derived Fungi Aspergillus allahabadii and Aspergillus ochraceopetaliformis