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As part of our research to discover novel bioactive natural products from marine microorganisms, five bagremycin analogues, including the previously unreported bagremycins F ( 1 ) and G ( 2 ), were isolated from a marine actinomycete Streptomyces sp. ZZ745. The structures of these compounds were determined by means of NMR spectroscopic analysis, HRESIMS data, and optical rotation. Both bagremycins F ( 1 ) and G ( 2 ) showed antibacterial activity against Escherichia coli , with MIC values of 41.8 and 61.7 μM, respectively.

New Antibacterial Bagremycins F and G from the Marine-Derived Streptomyces sp. ZZ745