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Three new 9,11-secosterols, pinnisterols A–C ( 1 – 3 ), were isolated from a gorgonian coral  Pinnigorgia  sp., collected off the waters of Taiwan. The structures of these compounds were elucidated on the basis of spectroscopic methods. The new sterols  1  and  3  displayed significant inhibitory effects on the generation of superoxide anions and the release of elastase by human neutrophils, and sterol  1  was found to show moderate cytotoxicity in hepatic stellate cells (HSCs).

Pinnisterols A–C, New 9,11-Secosterols from a Gorgonian Pinnigorgia sp.