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Fifteen participants (9 male, 6 female) received a total of 15 monolithic single restorations made from fully sintered (Y, Nb)-TZP (tetragonal zirconia polycrystal) block. The restorations were clinically evaluated for survival, success rate, and periodontal probing depths 6 months after the insertion of the restorations. Esthetic, functional, and biological evaluations were also performed over a 6-month follow-up period. The survival and success rates of the single-unit restorations were 100%. The periodontal probing depth values ranged from 1 to 3 mm. No complications with regard to functional and biological properties were observed after 6 months. The postoperative sensitivity was only a transient phenomenon. The fully sintered (Y, Nb)-TZP single-unit restoration showed highly acceptable quality with successful clinical performance over 6 months.

Clinical Feasibility of Fully Sintered (Y, Nb)-TZP for CAD-CAM Single-Unit Restoration: A Pilot Study