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The anti-corrosion inhibition effect of itraconazole on copper (Cu) in 0.5 M H₂SO₄ is observed with variety of experimental methods, including electrochemical measurement, surface morphology analysis, and theoretical calculations. These experimental results all confirm that itraconazole exhibits excellent anti-corrosion performance in the certain temperatures range (298 K⁻313 K) for copper in sulfuric acid solution. In addition, corresponding adsorption isothermal models were used to fit the adsorption behavior of itraconazole on the copper surface. The results show that the Langmuir adsorption model agrees best with the experimental results. The adsorption of itraconazole on the copper surface belongs to chemical and physical adsorption.

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Investigation the Corrosion Inhibition Effect of Itraconazole on Copper in H2SO4 at Different Temperatures: Combining Experimental and Theoretical Studies