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A composite material comprised of graphene nanoplatelet and silver particles (GNPs-AgPs) was used for the deposition of GNPs-AgPs' nanofilms with cold plasma on silk. α-Cyclodextrin was used as a modifier of the active surface of the disposable sensor. The disposable stochastic sensor was used in screening tests for the assay of heregulin-α in whole blood and tissue samples. The disposable stochastic sensor showed a low limit of determination (4.10 fg mL -1 ) and can be used with high sensitivity on a wide concentration range (4.10 fg mL -1 -0.04 µg mL -1 ). The screening method was validated against ELISA when good correlations (confirmed also by the t -test) were obtained.

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Sensitive Detection of Heregulin-α from Biological Samples Using a Disposable Stochastic Sensor Based on Plasma Deposition of GNPs–AgPs’ Nanofilms on Silk