English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

In the current study, an ethyl acetate extract from the endophytic fungus Aspergillus sp. SPH2 isolated from the stem parts of the endemic plant Bethencourtia palmensis was screened for its biocontrol properties against plant pathogens ( Fusarium moniliforme , Alternaria alternata, and Botrytis cinerea ), insect pests ( Spodoptera littoralis , Myzus persicae , Rhopalosiphum padi ), plant parasites ( Meloidogyne javanica ), and ticks ( Hyalomma lusitanicum ). SPH2 gave extracts with strong fungicidal and ixodicidal effects at different fermentation times. The bioguided isolation of these extracts gave compounds 1 - 3 . Mellein ( 1 ) showed strong ixodicidal effects and was also fungicidal. This is the first report on the ixodicidal effects of 1 . Neoaspergillic acid ( 2 ) showed potent antifungal effects. Compound 2 appeared during the exponential phase of the fungal growth while neohydroxyaspergillic acid ( 3 ) appeared during the stationary phase, suggesting that 2 is the biosynthetic precursor of 3 . The mycotoxin ochratoxin A was not detected under the fermentation conditions used in this work. Therefore, SPH2 could be a potential biotechnological tool for the production of ixodicidal extracts rich in mellein.

Bioactive Metabolites from the Endophytic Fungus Aspergillus sp. SPH2