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The present work describes a method to determine excitation function curves and, therefore, cross-sections, making use of the irradiation of liquid targets at distinct energies in a biomedical cyclotron. The method relies on the derivative of experimentally measured thick target yield curves to determine the corresponding excitation function curves. The technique is presented as a valid and practical alternative to the commonly used activation method combined with the stack monitor technique, whose implementation in liquid targets offers practical difficulties. The working principle is exemplified by presenting the results obtained for the clinically relevant 68Zn(p,n)68Ga and the 64Zn(p,α)61Cu nuclear reactions, obtained though the irradiation of liquid targets containing dissolved natural zinc.

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Experimental Determination of Excitation Function Curves through the Measurement of Thick Target Yields in Liquid Targets: The Examples of the 68Zn(p,n)68Ga and 64Zn(p,α)61Cu Nuclear Reactions