English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The HCO 3  - concentration in venous serum ([HCO 3  - ] s ) is a factor commonly used for detecting the body pH and metabolic conditions. To exactly detect [HCO 3  - ] s , the venous CO 2 pressure should be kept as it is in the vein. The [HCO 3  - ] s measurement is technically complicated to apply for huge numbers of almost heathy persons taking only basic medical examinations. The summation of [HCO 3  - ] s and the venous serum Cl - concentration ([Cl - ] s ) is approximately constant; therefore, we studied if [Cl - ] s could be a marker detecting metabolic conditions instead of [HCO 3  - ] s . Venous blood was obtained from persons taking basic medical examinations (the number of persons = 107,630). Older persons showed higher values of [Cl - ] s , fasting blood sugar (FBS), and glycated hemoglobin (HbA1c) than younger ones. [Cl - ] s showed positive correlation to age and negative correlation to FBS and HBA1c. The negative correlation of [Cl - ] s to FBS/HbA1c was obvious in persons with high FBS/HbA1c, leading us to an idea that persons with high FBS/HbA1c show high [HCO 3  - ] s , which might be caused by low activity of carbonic anhydrase in the lung observed in persons with diabetes mellitus under acidotic conditions. Taken together, an easily measured serum electrolyte, [Cl - ] s , could be a useful marker estimating metabolic conditions.

international journal of molecular sciences

Possibility of Venous Serum Cl− Concentration ([Cl−]s) as a Marker for Human Metabolic Status: Correlation of [Cl−]s to Age, Fasting Blood Sugar (FBS), and Glycated Hemoglobin (HbA1c)