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Nitrous oxide (N 2 O) is a dissociative anaesthetic that is sometimes used recreationally. The prevalence of N 2 O use is difficult to quantify but appears to be increasing. Research on N 2 O harms and application of harm reduction strategies are limited. The aim of this mixed method systematic review was to collate and synthesise the disparate body of research on recreational nitrous oxide use to inform harm reduction approaches tailored for young people.

A Systematic Review of Recreational Nitrous Oxide Use: Implications for Policy, Service Delivery and Individuals