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(1) Owing to their resistance resources, nurses can reduce the effects of stress, increase their commitment to work and improve their functioning in the face of challenges in the workplace. The aim of this study was to determine the mediatory role of a general sense of coherence and a sense of comprehensibility, manageability and meaningfulness correlated with global self-esteem and the perceived stress intensity in a group of Polish nurses aged 45–55 years. (2) The research using the diagnostic survey method was conducted on a group of 176 nurses (M = 49.1; SD = 3.1) working in seven hospitals located in Olsztyn (Poland). The following were used for data collection: Perceived Stress Scale - PSS-10, Rosenberg’s Self-Esteem Scale and Antonovsky’s Sense of Coherence (SOC-29) Questionnaire. (3) According to 21.02% of the nurses, their stress level at the workplace was low, 44.89% reported it was medium and 34.09% reported it was high. The self-esteem of nearly half of the nurses included in the study (48.30%) was at a medium level, 31.82% felt it was high and 19.89% felt it was low. The mediation analysis showed that a general sense of coherence and a sense of comprehensibility, manageability and meaningfulness have a mediator status in a correlation between global self-esteem and stress intensity. However, their mediatory role is partial. It is desirable for safe work environment promotion programmes to reinforce nurses’ personal resources, which can be helpful in coping with stressors.

Global Self-Esteem and Stress Intensity in a Group of Polish Nurses—A Mediatory Role of a Sense of Coherence