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This study describes key topics of discussions on Twitter at the intersection of vaping and COVID-19 and documents public reactions to announcements from authoritative health agencies. Twitter posts containing vaping and COVID-19-related terms were collected from 1 December 2019 to 3 May 2020 ( n  = 23,103 posts). Text classifiers and unsupervised machine learning were used to identify topics in posts. Predominant topics included  COVID-19 Respiratory Health  (18.87%),  COVID-19 Susceptibility  (17.53%),  Death  (10.07%),  Other COVID-19 Health Effects  (9.62%), and  Severity of COVID-19  (7.72%), among others. Public conversations on topics, such as  Severity of COVID-19 ,  Transmission ,  Susceptibility ,  Health Effects ,  Death , and  Smoking cessation , were shaped by announcements from U.S. and international health agencies. Armed with the insights from this study, medical providers should be prepared to discuss vaping-related health risks with their patients in the era of COVID-19. Misconceptions around vaping as a protective behavior from, and an effective treatment against, COVID-19 should also be corrected.

Vaping and COVID-19: Insights for Public Health and Clinical Care from Twitter