English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

This study aimed to investigate the association between traffic-related air pollution (TRAP) exposure and histone H3 modification among school children in high-traffic (HT) and low-traffic (LT) areas in Malaysia. Respondents' background information and personal exposure to traffic sources were obtained from questionnaires distributed to randomly selected school children. Real-time monitoring instruments were used for 6-h measurements of PM 10 , PM 2.5 , PM 1 , NO 2 , SO 2 , O 3 , CO, and total volatile organic compounds (TVOC). Meanwhile, 24-h measurements of PM 2.5 -bound black carbon (BC) were performed using air sampling pumps. The salivary histone H3 level was captured using an enzyme-linked immunosorbent assay (ELISA). HT schools had significantly higher PM 10 , PM 2.5 , PM 1 , BC, NO 2 , SO 2 , O 3 , CO, and TVOC than LT schools, all at p &lt; 0.001. Children in the HT area were more likely to get higher histone H3 levels ( z = -5.13). There were positive weak correlations between histone H3 level and concentrations of NO 2 ( r = 0.37), CO ( r = 0.36), PM 1 ( r = 0.35), PM 2.5 ( r = 0.34), SO 2 ( r = 0.34), PM 10 ( r = 0.33), O 3 ( r = 0.33), TVOC ( r = 0.25), and BC ( r = 0.19). Overall, this study proposes the possible role of histone H3 modification in interpreting the effects of TRAP exposure via non-genotoxic mechanisms.

international journal of environmental  research and public health/international journal of environmental research and public health

The Influence of Traffic-Related Air Pollution (TRAP) in Primary Schools and Residential Proximity to Traffic Sources on Histone H3 Level in Selected Malaysian Children