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Background : The present study aimed to investigate the incidence and characteristics of retinoblastoma in the overall population of Poland. Methods : The retrospective survey of both National Health Fund (NHF) and National Cancer Registry (NCR) databases were performed to identify all retinoblastoma cases in Poland in the years 2010-2017. Results : During 2010-2017, the mean age-standardised incidence of retinoblastoma (the unit of incidence is per 1,000,000 person-years) was 10.15 (95% CI 7.23-13.08) among children aged 0 to 4 years and 5.39 (95% CI 4.18-6.60) in those aged 0 to 9 years. During 2010-2014 (to allow 5 years of follow-up), the mean incidence of retinoblastoma by birth cohort analysis in Poland was 4.89 (95% CI 4.04-5.74) per 100,000 live births, corresponding to an incidence of 1 per 20,561 (95% CI 15,855-25,267) live births. In Poland, 14.6% of children with retinoblastoma had enucleation of the eye globe, 76.8% received different types of chemotherapy combined with focal treatment, 5.9% were treated with external beam radiotherapy, and 2.7% were treated with focal treatments only. Conclusions : The incidence of retinoblastoma and the pattern of medical management of retinoblastoma in Poland was similar to that reported in developed countries in Western Europe, Asia, and North America.

Incidence and Characteristics of Retinoblastoma in Poland: The First Nationwide Study 2010–2017