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It is too early to provide a clear answer on the impact of exposure to the second-hand aerosol of heated tobacco products (HTPs) in the planning of policy for smoke-free indoors legislation. Here, we conducted a preliminary study to evaluate indoor air quality with the use of HTPs. We first measured the concentration of nicotine and particulate matter (PM 2.5 ) in the air following 50 puffs in the use of HTPs or cigarettes in a small shower cubicle. We then measured these concentrations in comparison with the use equivalent of smoking 5.4 cigarettes per hour in a 25 m 3 room, as a typical indoor environment test condition. In the shower cubicle test, nicotine concentrations in indoor air using three types of HTP, namely IQOS, glo, and ploomTECH, were 25.9-257 μg/m 3 . These values all exceed the upper bound of the range of tolerable concentration without health concerns, namely 3 µg/m 3 . In particular, the indoor PM 2.5 concentration of about 300 to 500 μg/m 3 using IQOS or glo in the shower cubicle is hazardous. In the 25 m 3 room test, in contrast, nicotine concentrations in indoor air with the three types of HTP did not exceed 3 μg/m 3 . PM 2.5 concentrations were below the standard value of 15 μg/m 3 per year for IQOS and ploomTECH, but were slightly high for glo, with some measurements exceeding 100 μg/m 3 . These results do not negate the inclusion of HTPs within a regulatory framework for indoor tolerable use from exposure to HTP aerosol, unlike cigarette smoke.

Exposure Assessment of Environmental Tobacco Aerosol from Heated Tobacco Products: Nicotine and PM Exposures under Two Limited Conditions