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Vegetation cover plays a key role in terrestrial ecosystem; therefore, it is important for researchers to investigate the variation and influencing factors of vegetation cover. China has experienced a large-scale vegetation cover change in recent years. We summarized the literature of vegetation cover change and revealed how large-scale anthropogenic activities influence vegetation cover change in China. Afforestation and intensification of cropland played a key role in large-scale greening. Urbanization showed a “U” shape to influence vegetation cover change. Mining and reclamation, land abandonment and land consolidation, and regional natural protection all had a unique influence on the change of vegetation cover. Indeed, the large-scale vegetation cover change was caused by interaction of anthropogenic factors and part human-driven climate change. Anthropogenic factors influenced climate change to indirectly alter the condition of plant growth. Interaction between climate change and human activities influence on vegetation cover still needs to be further investigated in the future.

How Large-Scale Anthropogenic Activities Influence Vegetation Cover Change in China? A Review