English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Antibiotics are frequently detected in the aquatic environment due to their excessive usage and low-efficiency removal in wastewater treatment plants. This can provide the origin to the development of antibiotic-resistant genes in the microbial community, with considerable ecotoxicity to the environment. Among the antibiotics, the occurrence of ciprofloxacin (CIP) and amoxicillin (AMX) has been detected in various water matrices at different concentrations around the Earth. They are designated as emerging contaminants (ECs). Microalga Chlorella vulgaris (C. vulgaris) has been extensively employed in phycoremediation studies for its acclimatization property, non-target organisms for antibiotics, and the production of value-added bioproducts utilizing the nutrients from the wastewater. In this study, C. vulgaris medium was spiked with 5 mg/L of CIP and AMX, and investigated for its growth-stimulating effects, antibiotic removal capabilities, and its effects on the biochemical composition of algal cells compared to the control medium for 7 days. The results demonstrated that C. vulgaris adapted the antibiotic spiked medium and removed CIP (37 ± 2%) and AMX (25 ± 3%), respectively. The operating mechanisms were bioadsorption, followed by bioaccumulation, and biodegradation, with an increase in cell density up to 46 ± 3% (CIP) and 36 ± 4% (AMX), compared to the control medium. Further investigations revealed that, in the CIP stress-induced algal medium, an increase in major photosynthetic pigment chlorophyll-a (30%) and biochemical composition (lipids (50%), carbohydrates (32%), and proteins (65%)) was observed, respectively, compared to the control medium. In the AMX stress-induced algal medium, increases in chlorophyll-a (22%), lipids (46%), carbohydrates (45%), and proteins (49%) production were observed compared to the control medium. Comparing the two different stress conditions and considering that CIP is more toxic than AMX, this study provided insights on the photosynthetic activity and biochemical composition of C. vulgaris during the stress conditions and the response of algae towards the specific antibiotic stress. The current study confirmed the ability of C. vulgaris to adapt, bioadsorb, bioaccumulate, and biodegrade emerging contaminants. Moreover, the results showed that C. vulgaris is not only able to remove CIP and AMX from the medium but also can increase the production of valuable biomass usable in the production of various bioproducts.

Efficacy of Ciprofloxacin and Amoxicillin Removal and the Effect on the Biochemical Composition of Chlorella vulgaris