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We study densely defined unbounded operators acting between different Hilbert spaces. For these, we introduce a notion of symmetric (closable) pairs of operators. The purpose of our paper is to give applications to selected themes at the cross road of operator commutation relations and stochastic calculus. We study a family of representations of the canonical commutation relations (CCR)-algebra (an infinite number of degrees of freedom), which we call admissible. The family of admissible representations includes the Fock-vacuum representation. We show that, to every admissible representation, there is an associated Gaussian stochastic calculus, and we point out that the case of the Fock-vacuum CCR-representation in a natural way yields the operators of Malliavin calculus. We thus get the operators of Malliavin’s calculus of variation from a more algebraic approach than is common. We further obtain explicit and natural formulas, and rules, for the operators of stochastic calculus. Our approach makes use of a notion of symmetric (closable) pairs of operators. The Fock-vacuum representation yields a maximal symmetric pair. This duality viewpoint has the further advantage that issues with unbounded operators and dense domains can be resolved much easier than what is possible with alternative tools. With the use of CCR representation theory, we also obtain, as a byproduct, a number of new results in multi-variable operator theory which we feel are of independent interest

Infinite-dimensional Lie Algebras, Representations, Hermitian Duality and the Operators of Stochastic Calculus