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In this study, computational simulations and experiments were performed to investigate the mechanical behavior of the aorta wall because of the increasing occurrences of aorta-related diseases. The study focused on the deformation and strength of porcine and healthy human abdominal aortic tissues under uniaxial tensile loading. The experiments for the mechanical behavior of the arterial tissue were conducted using a uniaxial tensile test apparatus to validate the simulation results. In addition, the strength and stretching of the tissues in the abdominal aorta of a healthy human as a function of age were investigated based on the uniaxial tensile tests. Moreover, computational simulations using the ABAQUS finite element analysis program were conducted on the experimental scenarios based on age, and the Holzapfel–Gasser–Ogden (HGO) model was applied during the simulation. The material parameters and formulae to be used in the HGO model were proposed to identify the failure stress and stretch correlation with age.

applied sciences

Determination of the Material Parameters in the Holzapfel-Gasser-Ogden Constitutive Model for Simulation of Age-Dependent Material Nonlinear Behavior for Aortic Wall Tissue under Uniaxial Tension