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Accurately identifying the pixels of small organs or lesions from magnetic resonance imaging (MRI) has a critical impact on clinical diagnosis. U-net is the most well-known and commonly used neural network for image segmentation. However, the small anatomical structures in medical images cannot be well recognised by U-net. This paper explores the performance of the U-net architectures in knee MRI segmentation to find a relative structure that can obtain high accuracies for both small and large anatomical structures. To maximise the utilities of U-net architecture, we apply three types of components, residual blocks, squeeze-and-excitation (SE) blocks, and dense blocks, to construct four variants of U-net, namely U-net variants. Among these variants, our experiments show that SE blocks can improve the segmentation accuracies of small labels. We adopt DeepLabv3plus architecture for 3D medical image segmentation by equipping SE blocks based on this discovery. The experimental results show that U-net with SE block achieves higher accuracy in parts of small anatomical structures. In contrast, DeepLabv3plus with SE block performs better on the average dice coefficient of small and large labels.

Detecting Small Anatomical Structures in 3D Knee MRI Segmentation by Fully Convolutional Networks