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Goyazensolide, a biologically active natural product classified as a furoheliangolide, was transformed in a phthalimide derivative that showed an enhanced biological activity against Tripanosoma cruzi. The complex natural product was also reduced with high stereoselectivity by hydrogen/WilkinsonÃ¢Â€Â™s catalyst; an epimer of this product was obtained in the reduction with hydrogen/Pd-C

Reduction and Preparation of a Phthalimide Derivative from a Furo-heliangolide