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A method to reduce the nitro moiety in dimethyl 4-nitro-4-[1-[2(methoxycarbonyl)ethyl]]heptanedioate using a T-1 Raney nickel catalyst in an acidic environment is reported. The method avoids facile lactam formation

An Efficient, Self-Protecting Route to Dimethyl 4-Amino-4-[2-(methoxycarbonyl)ethyl]-heptanedioate HCl