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8-Substituted-2,5-dihydro-2-(4-N-dimethylaminophenyl)-4-(4-methoxyphenyl)-1,5-benzothiazepines (5a-e) have been synthesized by reacting 5-substituted-2-aminobenzene-thiols (1a-e) with 4-Ndimethylaminobenzal-4-methoxy acetophenone (2) in dry ethanol saturated with hydrogen chloride gas. The products were tested for purity by tlc and characterized by elemental analysis for carbon, hydrogen and nitrogen and IR, 1H NMR and mass spectral studies

molecules/molecules online/molecules annual

Syntheses of 1,5-Benzothiazepines. Part 20. Syntheses of 8-Substituted-2,5-dihydro-2-(4-N-dimethylaminophenyl)-4-(4-methoxyphenyl)-1,5-benzothiazepines