English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The objective of this study was to determine the effect of dietary lycopene supplementation on the growth performance, antioxidant enzyme activity of serum and liver, and gene expressions associated with Kelch-like ech-associated protein-1 ( Keap1 )/Nuclear Factor E2-related factor 2 ( Nrf2 ) pathway in liver of Arbor Acres broilers. A total of 288 1-day-old male broilers were randomly divided into 4 treatments with 6 replicates and 12 chickens for each replicate. The control group was fed with the basal diet, while the treated groups were fed with the basal diet with 10, 20, and 30 mg/kg lycopene in powder. Feed and water were provided  ad libitum  for 42 days. Compared with the control group, (a) the average daily gain increased ( p  = 0.002 vs.  p  = 0.001) and the feed conversion ratio decreased ( p  = 0.017 vs.  p  = 0.023) in groups treated with lycopene in the grower and whole phases, and the average daily feed intake was quadratically affected ( p  = 0.043) by lycopene in the grower phase; (b) the serum superoxide dismutase content was linearly affected ( p  = 0.035) by lycopene at 21 days; (c) the serum glutathione peroxidase content, superoxide dismutase content, and total antioxidant capability were higher ( p  = 0.014,  p  = 0.003, and  p  = 0.016, respectively) in the 30 mg/kg lycopene group at 42 days; (d) the liver glutathione peroxidase and superoxide dismutase contents in groups treated with lycopene were higher ( p  ≤ 0.001 vs.  p  ≤ 0.001) at 21 days; (e) the liver glutathione peroxidase content was higher ( p  ≤ 0.001) in the 20 and 30 mg/kg lycopene groups, at 42 days; (f) the mRNA expression levels of  Nrf2, superoxide dismutase 2, NAD(P)H quinone dehydrogenase 1 , and  heme oxygenase 1  genes were higher (21 days:  p  = 0.042,  p  = 0.021,  p  = 0.035, and  p  = 0.043, respectively; 42 days:  p  = 0.038,  p  = 0.025,  p  = 0.034, and  p  = 0.043, respectively) in the 20 and 30 mg/kg lycopene groups at 21 and 42 days. The 30 mg/kg lycopene concentration improved the growth performance, antioxidant enzyme activity in serum and liver, and gene expression in the  Keap1-Nrf2  signaling pathway of Arbor Acres broilers.

frontiers in veterinary science

Effect of Lycopene on the Growth Performance, Antioxidant Enzyme Activity, and Expression of Gene in the Keap1-Nrf2 Signaling Pathway of Arbor Acres Broilers