English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

Objectives:  We investigated a collection of strains belonging to the  Acinetobacter calcoaceticus - Acinetobacter baumannii  (ACB) complex obtained from a veterinary clinic with regard to their genetic relatedness, presence of antibiotic resistance genes and antimicrobial susceptibility profiles.   Methods:  Fifty-eight ACB-complex strains from animals treated at a veterinary clinic between 2006 and 2017, and seven strains collected from the hospital environment during 2012 were analyzed. Assignment to sequence types (ST) and international complexes (IC) was done by multilocus sequence typing (MLST) according to the Pasteur scheme. Genes encoding carbapenemases, aminoglycoside-modifying enzymes, macrolide-, quinolone- and co-trimoxazole resistance genes, the IS Aba1  element, virulence associated  intI1  genes and plasmid associated toxin-antitoxin markers were identified by microarray. Genes encoding  bla  OXA−51 -like carbapenemases were amplified by PCR and sequenced. Susceptibility profiles were determined by disc diffusion or by broth microdilution.   Results:  Among 50  A. baumannii  isolates from animals, two predominant clones were observed linked to CC1 ( n  = 27/54% of the isolates) and CC25 ( n  = 14/28%), respectively. Strains of IC I harbored  bla  OXA−69 ,  aac(3 ′ )-la, aadA1, sul1, intI1 , and  splA/T  genes. Isolates belonging to CC25 possessed  bla  OXA−64 . Six (12%) isolates belonging to CC2 and carrying  bla  OXA−66  were also noted. One isolate belonged to CC10 ( bla  OXA−68 ), one to CC149 ( bla  OXA−104 ), the remaining isolate was assigned to ST1220 and possessed  bla  OXA−116 . Of six environmental  A. baumannii , four (66.7%) belonged to CC25 ( bla  OXA−64 ), one (16.7%) to CC2 ( bla  OXA−66 ) and one to CC3 ( bla  OXA−71 ). Nine isolates (eight from animals and one environmental strain) were non- baumannii  strains and did not harbor  bla  OXA−51 -like genes. None of the isolates carried  bla  OXA−23 ,  bla  OXA−48 , or  bla  OXA−58 , and none were resistant to carbapenems.   Conclusions:  Clonal lineages of the veterinary  A. baumannii  isolates in our collection are identical to those globally emerging in humans but do not harbor  bla  OXA−23 .  A. baumannii  CC25 may be specific for this particular veterinary clinic environment.

frontiers in veterinary science

Phenotypic and Genotypic Characterization of Clinical Isolates Belonging to the Acinetobacter calcoaceticus-Acinetobacter baumannii (ACB) Complex Isolated From Animals Treated at a Veterinary Hospital in Switzerland