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The efficiency and level of drug quality supervision are highly related to the distorted or true reporting of new media, and the collusion or non-collusion of third-party testing agencies. Therefore, based on the co-regulation information platform, considering the strategic choices of local government, drug enterprises, third-party testing agencies and new media, this article constructs a four-party evolutionary game model of co-regulation supervision. The stable equilibrium points of each participant's strategic choices are solved. The stability of the strategic combination is analyzed by  Lyapunov's  first  method , and  Matlab 2020b  is used for simulation analysis to verify the influence of each decision variable on different players' strategic choices. The results show that, firstly, new media's true reporting can make up for the lack of supervision of drug enterprises by local government, and the greater the impact of new media reporting, the more active drug enterprises will be to produce high-quality drugs. Secondly, non-collusion of third-party testing agencies can improve the self-discipline ability of drug enterprises, encourage new media to report truthfully, and play the role of co-regulation supervision. Furthermore, the greater the probability of new media's true reporting, the more local government tend to be stricter, and the probability of strict supervision is positively related to the central government's accountability. Finally, increasing penalty for producing low-quality drugs and collusion will help standardize the behavior of drug enterprises and third-party testing agencies. This article enriches and expands the theoretical basis of the drug quality co-regulation supervision and proposes corresponding countermeasures and suggestions.

Drug Quality Co-regulation Supervision Strategy Considering Collusion Behavior With New Media Participation