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Purpose:  To compare the prevalence of computer vision syndrome in university students of different teaching modes during the SARS-CoV-2 outbreak period.   Methods:  A cross-sectional survey study using the validated Computer Vision Syndrome Questionnaire in Chinese medical students of Sichuan University who took classroom lectures and the same-grade foreign students from a Bachelor of Medicine and Bachelor of Surgery (MBBS) program who took online lectures with similar schedules.   Results:  A total of 137 responses from 63 Chinese students and 74 MBBS students were obtained. The highest frequency of digital screen time was 7-9 h (43.24%, 32/74) for MBBS students and 2-4 h (46.03%, 29/63) for Chinese students. The prevalence of computer vision syndrome among Chinese students and MBBS students were 50.79% and 74.32%, respectively ( P  = 0.004). The average numbers of reported symptoms were 5.00 ± 2.17 in Chinese students and 5.91 ± 1.90 in MBBS students ( P  = 0.01). The three most highly reported symptoms were “heavy eyelids” (53.97%), “dryness” (50.79%), and “feeling of a foreign body” (46.03%) in Chinese students and “dryness” (72.97%), “feeling of a foreign body” (62.16%), and “heavy eyelids” (58.11%) in MBBS students. The sum grades of computer vision syndrome had a moderate positive correlation with screen time (Spearman's correlation coefficient = 0.386,  P  < 0.001). The grades of symptoms of “feeling of a foreign body,” “heavy eyelids,” and “dryness” showed a weak positive correlation with screen time (Spearman's correlation coefficients were 0.220, 0.205, and 0.230, respectively).   Conclusion:  Online study may contribute to the prevalence of computer vision syndrome among university students.

Computer Vision Syndrome During SARS-CoV-2 Outbreak in University Students: A Comparison Between Online Courses and Classroom Lectures