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Background:  Little is known about the role of perceived neighborhood environment as a determinant of physical activity (PA) and sedentary time (ST) in understanding obesity-related health behaviors. We focus on a biracial, socioeconomically diverse population using objectively measured ST, which is under-represented in the literature.   Methods:  We examined the association between self-reported neighborhood perception (Likert-scale questions), PA using the Baecke questionnaire, and both non-sedentary time and ST using accelerometry from wave 4 of the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study ( n  = 2,167). After applying exclusion criteria, the sample size was  n  = 1,359 for analyses of self-reported PA and  n  = 404 for analyses of accelerometry data. Factor analysis identified key neighborhood characteristics to develop a total neighborhood perception score (NPS). Higher NPS indicated less favorable neighborhood perception. Linear regression was used to determine the relationship between NPS, PA, non-sedentary time, and ST.   Results:  Complete data were available for  n  = 1,359 [age 56.6(9.0) years, 59.5% female, 62.2% African American] for whom we identified four neighborhood perception factors: (1) concern about crime, (2) physical environment, (3) location of violent crime, and (4) social environment. Worsening perception of the overall neighborhood [β = −0.13 (SE = 0.03);  p  = 0.001], the physical environment [−0.11 (0.05);  p  = 0.03], and the social environment [−0.46 (0.07);  p  < 0.0001] were associated with decreased PA. Worsening perception of the overall neighborhood [1.14 (0.49);  p  = 0.02] and neighborhood social environment [3.59 (1.18);  p  = 0.003] were associated with increased ST over the day. There were no interactions for race, sex, poverty status, or economic index.   Conclusion:  Poor overall neighborhood perception, perceived social environment, and perceived neighborhood physical environment are associated with PA and ST in a multi-racial, socioeconomically diverse cohort of urban adults.   Clinical Trial Registration:  The HANDLS study is registered at  ClinicalTrials.gov  as NCT01323322.

Cross-Sectional Associations of Neighborhood Perception, Physical Activity, and Sedentary Time in Community-Dwelling, Socioeconomically Diverse Adults