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Background/Objective  Mental health problems are common among college students. This study sought to assess the prevalence and risk factors of depressive and anxiety symptoms and well-being among Chinese college students 9 months after initiation of the outbreak of COVID-19.    Method  A cross-sectional study ( N  = 3,951, mean age = 19.58) was conducted from October to December 2020. An online survey was used to collect socio-demographic data, and the symptoms of depression and anxiety and satisfaction with life using Disorder 7-Item Scale (GAD-7), the Patient Health Questionnaire 9-Item Scale (PHQ-9), and the 5-items Satisfaction with Life Scale (SWLS).    Results  The prevalence of depressive and anxiety symptoms was 59.35 and 54.34%, respectively, and the score of satisfaction with life was 20.51 ± 6.42 among Chinese college students during the pandemic. After controlling for covariates, students in urban areas (AOR = 0.73, 95% CI = 0.61–0.87), with good family economic levels (AOR = 0.77, 95% CI = 0.66–0.91), and having psychological counseling (AOR = 0.55, 95% CI = 0.42–0.73) were positively associated with depression symptoms; meanwhile, higher anxiety symptoms were observed among medical students (AOR = 0.81, 95% CI = 0.69–0.95). Besides, healthy lifestyle such as regular physical activity and diet was associated with depression and anxiety symptoms. Multiple linear models revealed that medical students (β = 0.479,  P  = 0.031), those with good family economic level by self-evaluation (β = 1.283,  P  &amp;lt; 0.001 for good; β = 3.013,  P  &amp;lt; 0.001 for general), good academic performance by self-evaluation (β = 1.786,  P  &amp;lt; 0.001 for good; β = 3.386,  P  &amp;lt; 0.001 for general), learning burden (β = 1.607,  P  &amp;lt; 0.001 for general; β = 2.117,  P  &amp;lt; 0.001 for light), regular physical activity (β = 0.859,  P  &amp;lt; 0.001), daily routine (β = 1.289,  P  &amp;lt; 0.001), diet (β = 1.714,  P  &amp;lt; 0.001), and sufficient sleep (β = 1.408,  P  &amp;lt; 0.001) had more score of SWLS (all β &amp;gt; 0,  P  &amp;lt; 0.05), while senior students (β = −1.053,  P =0.009), students having psychological counseling (β = −1.753,  P  &amp;lt; 0.001), and drinking (β = −0.743,  P  = 0.012) had lower satisfaction with life.    Conclusions  These findings suggest that more attention should be paid to psychological health among college students, especially during and after the COVID-19 outbreak. Policy makers and educators should help college students develop a healthy lifestyle with regular diet and exercise to promote the psychological health of college students.

Anxiety, Depression, and Satisfaction With Life Among College Students in China: Nine Months After Initiation of the Outbreak of COVID-19