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This study builds on the hypothesis put forth in  Boeckx and Benítez-Burraco (2014) , according to which the developmental changes expressed at the levels of brain morphology and neural connectivity that resulted in a more globular braincase in our species were crucial to understand the origins of our language-ready brain. Specifically, this paper explores the links between two well-known ‘language-related’ genes like  FOXP2  and  ROBO1  implicated in vocal learning and the initial set of genes of interest put forth in  Boeckx and Benítez-Burraco (2014) , with  RUNX2  as focal point. Relying on the existing literature, we uncover potential molecular links that could be of interest to future experimental inquiries into the biological foundations of language and the testing of our initial hypothesis. Our discussion could also be relevant for clinical linguistics and for the interpretation of results from paleogenomics.

Globularity and language-readiness: generating new predictions by expanding the set of genes of interest