English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Initially identified as a mammalian apoptosis suppressor, defender against apoptotic death 1 (DAD1) protein has conserved plant orthologs acting as negative regulators of cell death. The potential roles and action mechanisms of plant DADs in resistance against  Phytophthora  pathogens are still unknown. Here, we cloned  GmDAD1  from soybean and performed functional dissection.  GmDAD1  expression can be induced by  Phytophthora sojae  infection in both compatible and incompatible soybean varieties. By manipulating  GmDAD1  expression in soybean hairy roots, we showed that  GmDAD1  transcript accumulations are positively correlated with plant resistance levels against  P. sojae . Heterologous expression of  GmDAD1  in  Nicotiana benthamiana  enhanced its resistance to  Phytophthora parasitica .  NbDAD1  from  N. benthamiana  was shown to have similar role in conferring  Phytophthora  resistance. As an endoplasmic reticulum (ER)-localized protein, GmDAD1 was demonstrated to be involved in ER stress signaling and to affect the expression of multiple defense-related genes. Taken together, our findings reveal that  GmDAD1  plays a critical role in defense against  Phytophthora  pathogens and might participate in the ER stress signaling pathway. The defense-associated characteristic of  GmDAD1  makes it a valuable working target for breeding  Phytophthora  resistant soybean varieties.

GmDAD1, a Conserved Defender Against Cell Death 1 (DAD1) From Soybean, Positively Regulates Plant Resistance Against Phytophthora Pathogens