English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

PsAvr3c is an effector identified from oomycete plant pathogen  Phytophthora sojae  that causes soybean root and stem rot disease. Earlier studies have demonstrated that PsAvr3c binds to a novel soybean spliceosomal complex protein, GmSKRP, to reprogram the splicing of hundreds of pre-mRNAs and consequently subvert host immunity. PsAvr3c family genes are present in some other  Phytophthora  species, but their function remains unknown. Here, we characterized the functions of  PsAvh27b  ( PsAvr3c  paralog from  P. sojae ),  ProbiAvh89  and  PparvAvh214  (orthologs from  P. cinnamomi  var.  robiniae  and  Phytophthora parvispora , respectively). The study reveals that both PsAvh27b and ProbiAvh89 interact with GmSKRPs  in vitro , and stabilize GmSKRP1  in vivo . However, PparvAvh214 cannot interact with GmSKRPs proteins. The qRT-PCR result illustrates that the alternative splicing of pre-mRNAs of several soybean defense-related genes are altered in  PsAvh27b  and  ProbiAvh89  when over-expressed on soybean hairy roots. Moreover, PsAvr3c family members display differences in promoting  Phytophthora  infection in a SKRP-dependent manner. Overall, this study highlights that the effector-mediated host pre-mRNA alternative splicing occurs in other pathosystems, thus providing new probes to further dissect SKRP-mediated plant susceptibility.

Functional Analysis of PsAvr3c Effector Family From Phytophthora Provides Probes to Dissect SKRP Mediated Plant Susceptibility