English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Organ size regulation is dependent on the precise spatial and temporal regulation of cell proliferation and cell expansion. A number of transcription factors have been identified that play a key role in the determination of aerial lateral organ size, but their functional relationship to various chromatin modifiers has not been well understood. To understand how leaf size is regulated, we previously isolated the  oligocellula1  ( oli1 ) mutant of  Arabidopsis thaliana  that develops smaller first leaves than the wild type (WT) mainly due to a reduction in the cell number. In this study, we further characterized  oli1  leaf phenotypes and identified the  OLI1  gene as well as interaction partners of OLI1. Detailed characterizations of leaf development suggested that the cell proliferation rate in  oli1  leaf primordia is lower than that in the WT. In addition,  oli1  was associated with a slight delay of the progression from the juvenile to adult phases of leaf traits. A classical map-based approach demonstrated that  OLI1  is identical to  HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES15  ( HOS15 ).  HOS15 / OLI1  encodes a homolog of human transducin β-like protein1 (TBL1). TBL1 forms a transcriptional repression complex with the histone deacetylase (HDAC) HDAC3 and either nuclear receptor co-repressor (N-CoR) or silencing mediator for retinoic acid and thyroid receptor (SMRT). We found that mutations in  HISTONE DEACETYLASE9  ( HDA9 ) and a switching-defective protein 3, adaptor 2, N-CoR, and transcription factor IIIB-domain protein gene,  POWERDRESS  ( PWR ), showed a small-leaf phenotype similar to  oli1 . In addition,  hda9  and  pwr  did not further enhance the  oli1  small-leaf phenotype, suggesting that these three genes act in the same pathway. Yeast two-hybrid assays suggested physical interactions, wherein PWR probably bridges HOS15/OLI1 and HDA9. Earlier studies suggested the roles of HOS15, HDA9, and PWR in transcriptional repression. Consistently, transcriptome analyses showed several genes commonly upregulated in the three mutants. From these findings, we propose a possibility that HOS15/OLI1, PWR, and HDA9 form an evolutionary conserved transcription repression complex that plays a positive role in the regulation of final leaf size.

frontiers in plant science

OLIGOCELLULA1/HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES15 Promotes Cell Proliferation With HISTONE DEACETYLASE9 and POWERDRESS During Leaf Development in Arabidopsis thaliana