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Biophysics is best defined as a mindset than as a specific subject matter (Nobel, 1974; Phillips et al., 2008). The biophysicist strives to quantify biological processes and to analyze them in terms of universal physico-chemical principles such as mass conservation, force balance, and thermodynamic equilibrium. Biophysics has played an important role in the growth of biology, especially in elucidating how the folded structure of proteins determines their function (Anfinsen, 1973; Dobson, 2003), but also in providing a solid foundation for electro-physiology, photosynthesis, respiration, and many other basic biological functions. The lasting contributions of physicists-turned-biologists such as Max Delbruck (Luria and Delbruck, 1943; Delbruck, 1970) and Francis Crick (Watson and Crick, 1953; Crick, 1970) illustrate the power of the physical perspective in biology.

Quantifying Green Life: Grand Challenges in Plant Biophysics and Modeling