English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background  Exercise training increases muscle VO 2  by increasing O 2  transport and O 2  uptake while cardiac output increase might be limited by the conformation of the chest in subjects with pectus excavatum (PE).    Aims  The aim of the present study was to investigate the influence of physical activity (PA) on functional parameters of cardiopulmonary performance and stroke volume obtained at Cardiopulmonary Exercise Test (CPET) in PE.    Methods and Procedures  A cohort of adolescents (15 with PE and 15 age- and sex-matched healthy controls, HC) underwent Cardiopulmonary Exercise Test (CPET) and administration of the International Physical Activity Questionnaire – Short Form (IPAQ-SF) with estimation of weekly PA (METs h –1 ⋅week –1 ). Determinants of CPET parameters were investigated with multivariable linear regression analysis.    Results  As expected, when compared to HC, PE had lower VO 2  max (37.2 ± 6.6 vs. 45.4 ± 6.4 mL⋅kg –1 ⋅min –1 ,  p  &amp;lt; 0.05), and VO 2 /HR max (O 2  pulse, 12.1 ± 2.4 vs. 16.2 ± 3.6 mL⋅min –1 ⋅bpm –1 ,  p  &amp;lt; 0.05). Importantly, physical activity level was a predictor of VO 2  max (adjusted for sex, body mass index, FEV 1 %, and presence of PE, β = 0.085; 95% Cl 0.010 to 0.160,  p  = 0.029) whereas O 2  pulse was independent from PA level (β = 0.035; 95% Cl −0.004 to 0.074).    Conclusion  Physical activity is a determinant of VO 2  max (cardiopulmonary performance), whereas it appears not to affect O 2  pulse (a measure of stroke volume at peak exercise) related to constrained diastolic filling in PE.

frontiers in physiology

Differential Influence of Physical Activity on Cardiopulmonary Performance and Stroke Volume Assessed at Cardiopulmonary Exercise Test in Pectus Excavatum: A Pilot Study