English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Toll receptors are involved in innate immunity of invertebrates. In this study, we identify and characterize two Toll genes (named  HcToll4  and  HcToll5 ) from triangle sail mussel  Hyriopsis cumingii. HcToll4  has complete cDNA sequence of 3,162 bp and encodes a protein of 909 amino acids.  HcToll5  cDNA is 4,501 bp in length and encodes a protein of 924 amino acids. Both deduced HcToll4 and HcToll5 protein contain signal peptide, extracellular leucine rich repeats (LRRs), and intracellular Toll/interleukin-1 (IL-1) receptor domains. Quantitative real-time PCR analysis revealed that  HcToll4  and  HcToll5  were largely distributed in the hepatopancreas and could be detected in the gills and mantle.  HcToll4  and  HcToll5  expression could respond to  Staphylococcus aureus, Vibrio parahaemolyticus , White spot syndrome virus (WSSV) or Poly I:C challenge. RNA interference by siRNA results showed that  HcToll4  and  HcToll5  were involved in the regulation of  theromacin  ( HcThe ) and  whey acidic protein  ( HcWAP ) expression. Based on these results,  HcToll4  and  HcToll5  might play pivotal function in  H. cumingii  innate immune response.

Cloning and Analysis of Gene Expression of Two Toll Receptors in Freshwater Pearl Mussel Hyriopsis cumingii