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Blood flow restriction (BFR) alone or in combination with exercise has been shown to result in favorable effects on skeletal muscle function and morphology (Loenneke et al., 2012a). BFR is a stimulus commonly applied with specialized pressure cuffs placed at the top of a limb which are inflated to a set pressure throughout exercise. The pressure applied should be high enough to occlude venous return from the muscle but low enough to maintain arterial inflow into the muscle. Throughout the literature several different methods are applied with respect to setting the BFR pressure, however, many of these appear methodologically flawed. The purpose of the current manuscript is to discuss the importance of setting BFR cuff pressure based on appropriate factors. This manuscript will focus on applying pressures to the lower limbs because the majority of the data has been collected on the lower body.

Blood flow restriction pressure recommendations: a tale of two cuffs