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Anastasios Ioannidis, Maria Magana, Cristian G. Bologa, Tudor I. Oprea, Ian T. Paulsen and George P. Tegos* 1 Department of Nursing, Faculty of Human Movement and Quality of Life Sciences, University of Peloponnese, Sparta, Greece 2 Department of Clinical Microbiology, Athens Medical School, Aeginition Hospital, Athens, Greece 3 Translational Informatics Division, Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM, USA 4 Department of Systems Biology, Center for Biological Sequence Analysis, Technical University of Denmark, Lyngby, Denmark 5 Department of Chemistry and Biomolecular Sciences, Macquarie University, NSW, Australia 6 Torrey Pines Institute for Molecular Studies, Port St. Lucie, FL, USA 7 Department of Dermatology, Harvard Medical School, Boston, MA, USA 8 Wellman Center for Photomedicine, Massachusetts General Hospital, Boston MA, USA *Correspondence: gtegos@tpims.org

Defining the microbial effluxome in the content of the host-microbiome interaction