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To use a quantitative approach to examine the effects of family interventions on physical activity (PA) and sedentary behavior (SB) in children aged 2. 5–12 years.   Methods:  PubMed, OVID, Web of Science, and others were searched from their inception to May 2020. Intervention studies that examined the effects of family interventions on PA among children aged 2.5–12 years were included in this meta-analysis. Lastly, subgroup analyses were conducted to examine the potential modifying effects of family intervention's characteristics and study quality.   Results:  Eleven articles met the inclusion criteria for this review. Studies investigated a range of PA outcomes, including moderate-to-vigorous PA (MVPA), total PA (TPA), daily steps, and SB levels. Meta-analysis showed that family intervention had a significant effect on PA [standardized mean difference (SMD) = 0.10; 95% CI = 0.01–0.19], especially for daily steps [weight means difference (WMD) = 1,006; 95% CI = 209–1,803], but not for SB (WMD = −0.38; 95% CI = −7.21–6.46). Subgroup analyses indicated the improvements in PA occurred when children were 6–12 years old, intervention focused on PA only, intervention duration ≤ 10 weeks, and “low risk of bias” study performed.   Conclusions:  Family intervention may be a promising way to promote children's PA levels, especially for daily steps.   Trial Registration:  Meta-analysis protocol was registered on PROSPERO: CRD42020193667.

Effects of Family Intervention on Physical Activity and Sedentary Behavior in Children Aged 2.5–12 Years: A Meta-Analysis