English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Lychee pulp phenolics (LPP) is mainly catabolized in the host colon, increasing the abundances of  Bacteroides  and  Lactobacillus . Herein, five selected gut microbial strains ( Bacteroides uniformis, B. thetaiotaomicron, Lactobacillus rhamnosus, L. plantarum , and  L. acidophilus ) were separately incubated with LPP to ascertain the specific strains participating in phenolic metabolism and the corresponding metabolites. The results indicated that  B. uniformis, L. rhamnosus , and  L. plantarum  were involved in LPP utilization, contributing to 52.37, 28.33, and 45.11% of LPP degradation after 48 h fermentation, respectively. Unprecedentedly, the metabolic pathway of the major phenolic compound quercetin-3- O -rutinose-7- O -α-L-rhamnoside by  L. plantarum , appeared to be the direct fission of C-ring at C2–O1 and C3–C4 bonds, which was proved from the occurrence of two substances with the deprotonated molecule [M–H] −  ion at  m/z  299 and 459, respectively. Meanwhile, it was fully confirmed that  B. uniformis  participated in the catabolism of isorhamnetin glycoside and procyanidin B2. In the  B. uniformis  culture, kaempferol was synthesized through dehydroxylation of quercetin which could be catabolized into alphitonin by  L. rhamnosus . Furthermore, LPP metabolites exerted higher antioxidant activity than their precursors and gave clues to understand the interindividual differences for phenolic metabolism by gut microbiota.

Novel Catabolic Pathway of Quercetin-3-O-Rutinose-7-O-α-L-Rhamnoside by Lactobacillus plantarum GDMCC 1.140: The Direct Fission of C-Ring