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Background:  Dietary guidelines have shifted emphasis from single nutrients to food patterns, food groups, and dietary ingredients. Nutrient profiling models need to do the same.   Methods:  Dietary intake data for 23,643 persons aged >2 years came from the 2011–2016 National Health and Examination Survey (NHANES 2011-16). Healthy Eating Index HEI-2015 was the diet quality measure. The new Nutrient Rich Food hybrid score (NRFh) was based on three subscores. The subscore based on x nutrients to encourage was defined as NRx. The subscore based on y MyPlate food groups to encourage was MPy. The negative subscore based on z nutrients to limit was LIMz. The final algorithm was NRFh(x.y.z) = NRx + MPy − LIMz. The selection of NRFh model components from among 16 nutrients and five food groups was based on regression analyses.   Results:  We conducted a total of 2,162,720 iterative regression analyses against HEI-2015 diet quality scores. NRF scores based on 16 nutrients accounted for up to 66% of the variance, whereas scores based on 5 MP food groups accounted for 50%. The new NRFh3:4:3 score with six nutrients and four food groups (fiber, potassium, PUFA+MUFA; whole grains, dairy, fruit, nuts and seeds; saturated fat, added sugar, sodium) explained 72%. The new NRFh4:3:3 score with seven nutrients and three food groups (protein, fiber, potassium, PUFA+MUFA; whole grain, dairy, fruit; saturated fat, added sugar, sodium;) also explained 72%. In both NRFh models, regressions remained significant for each population subgroup examined.   Conclusion:  The NRFh3:4:3 and NRFh4:3:3 models correlated well with HEI-2015 scores, a measure of diet quality that tracks compliance with Dietary Guidelines. Hybrid NP models based on nutrients and food groups could become part of dietary guidance.

New Nutrient Rich Food Nutrient Density Models That Include Nutrients and MyPlate Food Groups