English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background:  Although recent studies point to the involvement of the primary motor cortex in postural control, it is unknown if age-related deterioration of postural control is associated with changes in motor cortical circuits. We examined the interaction between age and sensory condition in the excitability of intracortical motor pathways as indexed by short-interval intracortical inhibition (SICI) and intracortical facilitation (ICF) during standing.   Methods:  We used magnetic brain stimulation to evoke SICI and ICF in 11 young (range 21–25 years) and 12 healthy old adults (range 60-74 years) while they stood on a rigid platform or foam, with the eyes open or closed.   Results:  There was an overall age-related 43% reduction in SICI ( p  = 0.001). SICI lessened when standing on foam in old (31%) but not in young (1%) adults (condition × group interaction,  p  = 0.049). This reduction was associated with increases in center of pressure velocity ( r  = -0.648,  p  = 0.043). Age ( p  = 0.527) and sensory conditions ( p  = 0.325) did not affect ICF.   Conclusion:  Motor cortical circuits controlling leg muscles are modulated differently in healthy old vs. young adults during upright posture. Future experiments will clarify whether this difference mediates impaired postural control or serves as a compensatory mechanism to counteract postural instability.

Age-related decrease in motor cortical inhibition during standing under different sensory conditions