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Surface modified bioactive virus-mimicking organic nanovesicles represent themselves as complex biomimetic structures that have abilities to dissect the functions of individual entities in a complex biochemical system. The customized surface of nanovesicles from (glyco)dendrimersomes has structural modifications that contribute to manifest the SARS-CoV-2 and host pathogenic molecular interactions that help the virus to evade the human immune system. Nanovesicles also have a potential role in dynamic biomedical applications such as designing galectin targeting drugs, evaluation of antibodies to design antiviral therapeutics or vaccines and targeted delivery of drugs.

frontiers in molecular biosciences

Bioactive Virus-Mimicking Nanovesicles From Dendrimersomes: A Novel Approach to Understanding SARS-CoV-2 Host-Interactions to Better Design Therapeutics