English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The objective of this study was to investigate associations between gastrointestinal microbiota and protein metabolism of lambs infected with  Haemonchus contortus . Sixteen male Ujumqin lambs (initial body weight = 32.4 ± 3.9 kg) were dewormed and randomly assigned to 2 equal groups, to be infected or not infected with  Haemonchus contortus  (GIN and CON, respectively). The experiment lasted 77 days. The GIN lambs had lower packed cell volume (PCV) and increased wormegg count (WEC) after 14 days. Furthermore, in infected lambs, there were decreases in apparent digestibility of dry matter ( P  = 0.011), crude protein ( P  = 0.004) and ether extract ( P  = 0.007), as well as decreased ruminal pepsin ( P  &amp;lt; 0.001) and lipase ( P  = 0.032) activity but increased ruminal α-amylase ( P  = 0.004) and cellulase activity ( P  = 0.002), and decreased jejunal α-amylase activity ( P  = 0.033). In addition, infection with  H. contortus  decreased alpha diversity of the gastrointestinal microbial community in the rumen, abomasum and duodenum, although microbiota associated with carbohydrate and proteolytic metabolism were increased and up to 32 KEGG pathways in the duodenum were predicted to be significantly affected. In conclusion,  H. contortus  infection in lambs altered the gastrointestinal microbial community composition and disturbed protein digestion and allocation of absorbed amino acids. These results provided insights into consequences of  H. contortus  infection in lambs and could facilitate development of novel nutritional strategies to improve animal health.

Haemonchus contortus Infection Alters Gastrointestinal Microbial Community Composition, Protein Digestion and Amino Acid Allocations in Lambs