English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Increasing evidence has indicated that oxidative stress is associated with the health of infants.  Bifidobacterium , especially  B. longum  subsp.  longum  strains, are abundant in the gut microbiota of infants, which may have the potential to ameliorate oxidative damage. Thus, this study aimed to isolate and screen  B. longum  subsp.  longum  strains with probiotic characters and antioxidant properties as infants’ dietary supplements. In this study, 24  B. longum  subsp.  longum  strains were isolated from 15 healthy infants identified  via  16S rRNA and heat shock protein 60 ( hsp 60) sequences.  B. longum  subsp.  longum  B13, F2, K4, K5, K10, K13, and K15 strains were selected based on high values obtained from autoaggregation, hydrophobicity, and adhesion assays to HT-29 cells. Among these seven strains,  B. longum  subsp.  longum  F2, K5, K10, and K15 were selected according to the high tolerance of gastrointestinal tract conditions compared to  Bifidobacterium animalis  subsp.  lactis  BB-12. Among these four strains,  B. longum  subsp.  longum  K5 was susceptible to common antibiotics and showed the highest intestinal epithelial cell proliferation of CCD 841 CoN. Additionally,  B. longum  subsp.  longum  K5 showed a strong antioxidant capacity, and its supernatant exhibited better activity of reducing power, hydroxyl radical scavenging, and DPPH radical scavenging than that of the intact cells with cell-free extracts. The findings indicated that  B. longum  subsp.  longum  K5 could be used as a probiotic candidate in infant nutrition.

Identification, Characterization, and Antioxidant Potential of Bifidobacterium longum subsp. longum Strains Isolated From Feces of Healthy Infants