English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The fungal pathogen,  Colletotrichum higginsianum , causes a disease called anthracnose on various cruciferous plants. Here, we characterized a  Saccharomyces cerevisiae CDC 25 ortholog in  C. higginsianum , named  ChCDC25  (CH063_04363). The  ChCDC25  deletion mutants were defective in mycelial growth, conidiation, conidial germination, appressorial formation, and invasive hyphal growth on  Arabidopsis  leaves, resulting in loss of virulence. Furthermore, deletion of  ChCDC25  led to increased sensitivity to cell wall stress and resulted in resistance to osmotic stress. Exogenous cyclic adenosine monophosphate (cAMP) and IBMX treatments were able to induce appressorial formation in the  ChCDC25  mutants, but abnormal germ tubes were still formed. The results implied that  ChCDC25  is involved in pathogenicity by regulation of cAMP signaling pathways in  C. higginsianum . More importantly, we found that ChCDC25 may interact with Ras2 and affects Ras2 protein abundance in  C. higginsianum . Taken together,  ChCDC25  regulates infection-related morphogenesis and pathogenicity of  C. higginsianum.  This is the first report to reveal functions of a  CDC 25 ortholog in a hemibiotrophic phytopathogen.

ChCDC25 Regulates Infection-Related Morphogenesis and Pathogenicity of the Crucifer Anthracnose Fungus Colletotrichum higginsianum