English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Bioprospecting natural products in marine bacteria from fjord environments are attractive due to their unique geographical features. Although,  Actinobacteria  are well known for producing a myriad of bioactive compounds, investigations regarding fjord-derived marine  Actinobacteria  are scarce. In this study, the diversity and biotechnological potential of  Actinobacteria  isolated from marine sediments within the Comau fjord, in Northern Chilean Patagonia, were assessed by culture-based approaches. The 16S rRNA gene sequences revealed that members phylogenetically related to the  Micrococcaceae, Dermabacteraceae, Brevibacteriaceae, Corynebacteriaceae, Microbacteriaceae, Dietziaceae, Nocardiaceae , and  Streptomycetaceae  families were present at the Comau fjord. A high diversity of cultivable  Actinobacteria  (10 genera) was retrieved by using only five different isolation media. Four isolates belonging to  Arthrobacter, Brevibacterium, Corynebacterium  and  Kocuria  genera showed 16S rRNA gene identity <98.7% suggesting that they are novel species. Physiological features such as salt tolerance, artificial sea water requirement, growth temperature, pigmentation and antimicrobial activity were evaluated.  Arthrobacter, Brachybacterium, Curtobacterium, Rhodococcus , and  Streptomyces  isolates showed strong inhibition against both Gram-negative  Pseudomonas aeruginosa, Escherichia coli  and  Salmonella enterica  and Gram-positive  Staphylococcus aureus, Listeria monocytogenes . Antimicrobial activities in  Brachybacterium, Curtobacterium , and  Rhodococcus  have been scarcely reported, suggesting that non-mycelial strains are a suitable source of bioactive compounds. In addition, all strains bear at least one of the biosynthetic genes coding for NRPS (91%), PKS I (18%), and PKS II (73%). Our results indicate that the Comau fjord is a promising source of novel  Actinobacteria  with biotechnological potential for producing biologically active compounds.

Exploring the Diversity and Antimicrobial Potential of Marine Actinobacteria from the Comau Fjord in Northern Patagonia, Chile