English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Antibiotic resistance in bacteria isolated from non-healthcare environments, is a potential problem to public health. In our survey a total of 71 coagulase negative staphylococci (CNS) belonging to 11 different species were isolated from three large hotels in London, UK. The most prevalent species was  Staphylococcus haemolyticus , with  S. hominis, S. warneri, S. cohnii , and  Staphylococcus epidermidis  commonly detected. Antimicrobial susceptibilities and carriage of the  mecA  gene were determined for all of these isolates. Most (85.9%) staphylococci were resistant to multiple antibiotics with all displaying increased susceptibility toward penicillin, fusidic acid, erythromycin, and cefepime. Twenty-one (29.5%) of the isolates were  mecA  positive, however MIC values to oxacillin, normally associated with the carriage of  mecA , varied widely in this group (from 0.06 to 256 mg/L). Fifteen of the twenty-one  mecA  positive isolates carried SCC mec  of these seven were type V, one type I, one type II, and one type IV. Additionally, five of these 15 isolates carried a previously unreported type, 1A, which involves an association between class A  mec  complex and  ccr  type 1. The remaining six of the 21 isolates were non-typeable and carried a combination of class A  mec  complex and  ccrC . In addition to this, we also report on new MLST types which were assigned for five  S. epidermidis  isolates. Four out of these five isolates had MICs between 0.06 and 256 mg/L to oxacillin and would be regarded as clinically susceptible but one isolate had a high oxacillin MIC of 256 mg/L. We demonstrated widespread multiple drug resistance among different staphylococcal species isolated from non-healthcare environments highlighting the potential for these species to act as a reservoir for methicillin and other forms of drug resistance.

Antibiotic resistance and mecA characterization of coagulase-negative staphylococci isolated from three hotels in London, UK