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Malaria remains a serious health concern across the globe. Historically neglected, non- Falciparum  human malarias were put back on the agenda by a paradigm shift in the fight against malaria from malaria control to malaria eradication. Here, we review the modeling of the relapsing parasites  Plasmodium vivax  ( P. vivax ) and  Plasmodium ovale  ( P. ovale ) in non-human primates with a specific focus on the contribution of these models to our current understanding of the factors that govern parasite-host interactions in  P. vivax  and  P. ovale  parasite biology and pathophysiology.

frontiers in cellular and infection microbiology

Parasite-Host Interaction and Pathophysiology Studies of the Human Relapsing Malarias Plasmodium vivax and Plasmodium ovale Infections in Non-Human Primates